The mission of the Institute for Therapeutic Innovation (ITI) is to develop optimized chemotherapy for medically important infectious diseases. In contradistinction to other laboratories, ITI does not focus upon a specific pathogen, but we apply the same therapeutic principles to many different pathogens. Examples include nosocomial pathogens (Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella species, and MRSA), tuberculosis, Select Agents, Pandemic Influenza, HIV, Hepatitis C and other bacterial and viral pathogens. We have developed unique and innovative model systems, including the hollow fiber infection model to probe for optimized drug regimens that kill pathogens and suppress resistance emergence. Distinctively, we apply cutting edge mathematical models to these data. This allows rapid identification of optimal regimens. This work is done to provide the best care for seriously infected patients.
The Institute for Therapeutic Innovation is a growing research institution of the College of Medicine, which is part of University of Florida’s Health Science Center, the largest medical education center in the southeast. You can also find our Organizational Chart here.